Universities must become active launchpads for innovation
We are in an era of unprecedented technological advancement. Yet American universities — long considered beacons of innovation — are facing an equally unprecedented crisis of confidence.
The Edelman Trust Barometer reveals a steady erosion of public trust across all pillars of society, with confidence in higher education falling to its lowest level ever. Critics from across the political spectrum increasingly label universities as elitist, self-interested, out-of-touch and unaccountable.
While these criticisms deserve serious attention, the current remedies — especially cutting research funding and laying off young research staff — carry significant risk.
The backbone of America’s research and development enterprise is a unique partnership between government and universities, a model with deep historical roots. Since the founding of institutions like MIT in 1861 and the development of the America research university model by Johns Hopkins in 1876, universities have been mandated to advance the nation’s “useful arts and manufactures.” This mission thrives on sustained investment and shared goals — between governments and universities, supported and amplified by philanthropic and industrial partners — shaping a research system that is the envy of the world.
Studies estimate that university-initiated innovation, alongside skilled workforce development, has driven about half of U.S. economic growth since World War II.
This university-government alignment is not simply a driver of prosperity; it is fundamental to American security. Undermining this critical bond jeopardizes our national security and interests. This reliance is clearly seen in the Department of Defense, which depends heavily on university research for advancements shaping the future battlefield, spanning fields like quantum sensors, self-healing materials and transformative aerospace engineering.
The need to strengthen our research universities comes at a moment when, according to a National Academies report, the U.S. “no longer has a monopoly on the top science.” Other nations are aggressively investing to challenge America’s lead in all aspects of research and development. China has massively ramped up research and development funding and now produces science at an unprecedented rate and scale, aiming to dominate sectors like AI, biotech, hypersonics and energy storage. China now nearly equals the U.S. in total research and development expenditures, and its whole-of-nation innovation push means America must run faster, not slower, in supporting science if we are to stay in the race.
The traditional contributions of universities — advancing knowledge through research and patents — remain fundamental to America’s economic and national security dynamism. These activities ensure a pipeline of talent and the diffusion of ideas, demonstrated by the fact that only the top 25 U.S. research universities contribute a very large portion of all U.S. university patents and train more first-time inventors than any other sector. However, as annual investment in university research and development climbs past the $100 billion mark, relying solely on these established mechanisms is no longer enough.
To maintain their relevance and continue to support our national security, universities must codify translation and entrepreneurship as a crucial pathway for making a difference. Research labs must move beyond passive spillovers and become active launchpads for new companies that leverage federally funded research.
University research translation is at best a serendipitous process. Making it more systematic represents an enormous opportunity for both more economic growth and better solutions to pressing national priorities. At a time when universities are on trial for being a resource drain, efforts to increase translation activity are desperately needed. We must make sure that the American public hears loud and clear about our focus on real-world impact.
Through a program MIT started five years ago called Proto Ventures, teams are turning breakthroughs made in tech labs into real-world solutions that can help all Americans. Proto Ventures is designed to actively leverage research, much of which is supported by taxpayer dollars, into impactful, sustainable businesses — rather than just hoping it happens.
To build companies from the ground up, we’ve brought a proactive and comprehensive approach to venture creation. We identify a technological field, industry or strategic challenge that is ripe for exploration. A dedicated small team then secures the agreement of our faculty in the relevant lab or center, and we bring in experienced venture builders. They and the wider Proto Ventures team do the essential work of identifying a robust pipeline of potential opportunities, reducing unsuccessful paths and propelling forward the ones with real potential.
As ideas solidify, we help teams of founders form and eventually leave the university and start to grow. In that way, Proto Ventures builds companies to change the world within a framework of shared interest with the funders (often the government) and focused on problems that matter to our shared future.

Programs like Proto Ventures show that universities aren’t simply about education and research, although those are of central importance; they can also prioritize and configure entrepreneurial processes to increase real-world impact and directly contribute to national security and economic growth.
By bridging the gap between groundbreaking research and tangible outcomes, universities can address their critics, strengthen the nation and focus on their highest purpose: advancing human progress through knowledge and innovation.
Gene R. Keselman is a lecturer at MIT School of Management, the executive director of MIT Mission Innovation Experimental and managing director of MIT’s Proto Ventures. He is also a colonel in the U.S. Air Force Reserve. Dame Fiona Murray is the William Porter professor of entrepreneurship and associate dean of innovation at the MIT School of Management. She is vice chair of the NATO Innovation Fund.
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