Well-Being Longevity

Heart inflammation in young adults higher than expected following mRNA vaccines, preliminary data suggests

Story at a glance

  • Data from the Centers for Disease Control and Prevention’s vaccine safety monitor system shows there have been 275 reported cases of myocarditis or pericarditis in 16- to 24-year-old patients as of May 31.
  • Most cases appear to occur in men.
  • A causal link to mRNA vaccines and heart inflammation issues has yet to be established, and health officials maintain the benefits of receiving the critical shot outweigh the risks.

Preliminary findings suggest the number of heart inflammation cases in people ages 16 to 24 following the second dose of mRNA COVID-19 vaccines is higher than expected. 

Limited data from the Centers for Disease Control and Prevention’s (CDC) vaccine safety monitor system shows there have been 275 reported cases of myocarditis or pericarditis — inflammation conditions in the heart— in 16- to 24-year-old patients as of May 31. Most cases appear to occur in men. 


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According to a CDC presentation prepared for a Food and Drug Administration (FDA) advisory panel meeting, the expected number of heart inflammation cases was somewhere between 10 and 102. 

A total of 475 cases of myocarditis or pericarditis were recorded in patients aged 30 and younger. The data shows at least 81 percent of patients had a full recovery from their symptoms. 

The CDC last month began investigating whether the Pfizer and Moderna COVID-19 vaccines could be linked to heart inflammation after a small number of teens and young adults experienced issues. 

A causal link to mRNA vaccines and heart inflammation issues has yet to be established, and health officials maintain the benefits of receiving the critical shot outweigh the risks. 


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